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Sox9 Gene Transfer Enhanced Regenerative Effect of Bone Marrow Mesenchymal Stem Cells on the Degenerated Intervertebral Disc in a Rabbit Model

OBJECTIVE: The effect of Sox9 on the differentiation of bone marrow mesenchymal stem cells (BMSCs) to nucleus pulposus (NP)-like (chondrocyte-like) cells in vitro has been demonstrated. The objective of this study is to investigate the efficacy and feasibility of Sox9-transduced BMSCs to repair the...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Zhang, Kai, Liu, Guangwang, Ding, Wei, Zhao, Changqing, Xie, Youzhuan, Yuan, Junjie, Sun, Xiaojiang, Li, Hua, Liu, Changsheng, Tang, Tingting, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972138/
https://www.ncbi.nlm.nih.gov/pubmed/24691466
http://dx.doi.org/10.1371/journal.pone.0093570