Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice

Basal cell carcinoma (BCC) belongs to the group of non-melanoma skin tumors and is the most common tumor in the western world. BCC arises due to mutations in the tumor suppressor gene Patched1 (Ptch). Analysis of the conditional Ptch knockout mouse model for BCC reveals that macrophages and dendriti...

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Detalles Bibliográficos
Autores principales: König, Simone, Nitzki, Frauke, Uhmann, Anja, Dittmann, Kai, Theiss-Suennemann, Jennifer, Herrmann, Markus, Reichardt, Holger M., Schwendener, Reto, Pukrop, Tobias, Schulz-Schaeffer, Walter, Hahn, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972151/
https://www.ncbi.nlm.nih.gov/pubmed/24691432
http://dx.doi.org/10.1371/journal.pone.0093555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972151/
https://www.ncbi.nlm.nih.gov/pubmed/24691432
http://dx.doi.org/10.1371/journal.pone.0093555

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