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An Engineered Non-Toxic Superantigen Increases Cross Presentation of Hepatitis B Virus Nucleocapsids by Human Dendritic Cells

Virus like particles (VLPs) are potent immunogens capable of priming strong protective antibody responses due to their repetitive structural arrangement and affinity for specific B cell receptors. By contrast, T cell responses to VLPs can be weak due to inefficient uptake and processing by antigen p...

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Detalles Bibliográficos
Autores principales: McIntosh, Julie D., Manning, Kristy, Chokshi, Shilpa, Naoumov, Nikolai V., Fraser, John D., Dunbar, P. Rod, Taylor, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972192/
https://www.ncbi.nlm.nih.gov/pubmed/24690680
http://dx.doi.org/10.1371/journal.pone.0093598