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An Engineered Non-Toxic Superantigen Increases Cross Presentation of Hepatitis B Virus Nucleocapsids by Human Dendritic Cells
Virus like particles (VLPs) are potent immunogens capable of priming strong protective antibody responses due to their repetitive structural arrangement and affinity for specific B cell receptors. By contrast, T cell responses to VLPs can be weak due to inefficient uptake and processing by antigen p...
Autores principales: | McIntosh, Julie D., Manning, Kristy, Chokshi, Shilpa, Naoumov, Nikolai V., Fraser, John D., Dunbar, P. Rod, Taylor, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972192/ https://www.ncbi.nlm.nih.gov/pubmed/24690680 http://dx.doi.org/10.1371/journal.pone.0093598 |
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