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Investigation of Genetic Variants, Birthweight and Hypothalamic-Pituitary-Adrenal Axis Function Suggests a Genetic Variant in the SERPINA6 Gene Is Associated with Corticosteroid Binding Globulin in the Western Australia Pregnancy Cohort (Raine) Study

BACKGROUND: The hypothalamic-pituitary-adrenal (HPA) axis regulates stress responses and HPA dysfunction has been associated with several chronic diseases. Low birthweight may be associated with HPA dysfunction in later life, yet human studies are inconclusive. The primary study aim was to identify...

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Detalles Bibliográficos
Autores principales: Anderson, Laura N., Briollais, Laurent, Atkinson, Helen C., Marsh, Julie A., Xu, Jingxiong, Connor, Kristin L., Matthews, Stephen G., Pennell, Craig E., Lye, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972221/
https://www.ncbi.nlm.nih.gov/pubmed/24691024
http://dx.doi.org/10.1371/journal.pone.0092957