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Investigation of Genetic Variants, Birthweight and Hypothalamic-Pituitary-Adrenal Axis Function Suggests a Genetic Variant in the SERPINA6 Gene Is Associated with Corticosteroid Binding Globulin in the Western Australia Pregnancy Cohort (Raine) Study
BACKGROUND: The hypothalamic-pituitary-adrenal (HPA) axis regulates stress responses and HPA dysfunction has been associated with several chronic diseases. Low birthweight may be associated with HPA dysfunction in later life, yet human studies are inconclusive. The primary study aim was to identify...
Autores principales: | Anderson, Laura N., Briollais, Laurent, Atkinson, Helen C., Marsh, Julie A., Xu, Jingxiong, Connor, Kristin L., Matthews, Stephen G., Pennell, Craig E., Lye, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972221/ https://www.ncbi.nlm.nih.gov/pubmed/24691024 http://dx.doi.org/10.1371/journal.pone.0092957 |
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