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Downregulation of HDAC1 Is Involved in the Cardiomyocyte Differentiation from Mesenchymal Stem Cells in a Myocardial Microenvironment

Under myocardial microenvironment, bone marrow-derived mesenchymal stem cells (MSCs) can transdifferentiate into cardiomyocytes (CMs). However, the role of histone deacetylase 1 (HDAC1) in this directed differentiation process remains unclear. The current study is to determine the acetylation regula...

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Detalles Bibliográficos
Autores principales: Lu, Dong-feng, Yao, Yan, Su, Zi-zhuo, Zeng, Zhao-hua, Xing, Xiao-wen, He, Zhi-yu, Zhang, Chunxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972222/
https://www.ncbi.nlm.nih.gov/pubmed/24690943
http://dx.doi.org/10.1371/journal.pone.0093222