5-Azacytidine Enhances the Radiosensitivity of CNE2 and SUNE1 Cells In Vitro and In Vivo Possibly by Altering DNA Methylation

The radioresistance of tumor cells remains a major cause of treatment failure in nasopharyngeal carcinoma (NPC). Recently, several reports have highlighted the importance of epigenetic changes in radiation-induced responses. Here, we investigated whether the demethylating agent 5-azacytidine (5-azaC...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Li, Ying-Qin, Liu, Na, Sun, Ying, He, Qing-Mei, Jiang, Ning, Xu, Ya-Fei, Chen, Lei, Ma, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972231/
https://www.ncbi.nlm.nih.gov/pubmed/24691157
http://dx.doi.org/10.1371/journal.pone.0093273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972231/
https://www.ncbi.nlm.nih.gov/pubmed/24691157
http://dx.doi.org/10.1371/journal.pone.0093273

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