The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines

The hexameric MCM complex is the catalytic core of the replicative helicase in eukaryotic and archaeal cells. Here we describe the first in vivo analysis of archaeal MCM protein structure and function relationships using the genetically tractable haloarchaeon Haloferax volcanii as a model system. Hf...

Descripción completa

Detalles Bibliográficos
Autores principales: Kristensen, Tatjana P., Maria Cherian, Reeja, Gray, Fiona C., MacNeill, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972481/
https://www.ncbi.nlm.nih.gov/pubmed/24723920
http://dx.doi.org/10.3389/fmicb.2014.00123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972481/
https://www.ncbi.nlm.nih.gov/pubmed/24723920
http://dx.doi.org/10.3389/fmicb.2014.00123

Ejemplares similares