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ROS-GC interlocked Ca(2+)-sensor S100B protein signaling in cone photoreceptors: review

Photoreceptor rod outer segment membrane guanylate cyclase (ROS-GC) is central to visual transduction; it generates cyclic GMP, the second messenger of the photon signal. Photoexcited rhodopsin initiates a biochemical cascade that leads to a drop in the intracellular level of cyclic GMP and closure...

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Detalles Bibliográficos
Autores principales: Sharma, Rameshwar K., Makino, Clint L., Hicks, David, Duda, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972482/
https://www.ncbi.nlm.nih.gov/pubmed/24723847
http://dx.doi.org/10.3389/fnmol.2014.00021