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E-cadherin–downregulation and RECK-upregulation are coupled in the non-malignant epithelial cell line MCF10A but not in multiple carcinoma-derived cell lines

Expression of a mesenchymal phenotype is often associated with invasive/metastatic behaviors of carcinoma cells. Acquisition of a mesenchymal phenotype by a carcinoma cell is known as epithelial-mesenchymal transition (EMT). The membrane-anchored matrix metalloproteinase-regulator RECK is abundant i...

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Detalles Bibliográficos
Autores principales: Yuki, Kanako, Yoshida, Yoko, Inagaki, Ryosaku, Hiai, Hiroshi, Noda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972504/
https://www.ncbi.nlm.nih.gov/pubmed/24691523
http://dx.doi.org/10.1038/srep04568