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Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling

12-O-tetradecanoylphorbol-13-acetate (TPA) activates multiple signaling pathways, alters gene expression and causes leukemic cell differentiation. How TPA-induced genes contribute to leukemic cell differentiation remains elusive. We noticed that chromosome 7 open reading frame 41 (C7ORF41) was a TPA...

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Detalles Bibliográficos
Autores principales: Sun, X, Lu, B, Hu, B, Xiao, W, Li, W, Huang, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972703/
https://www.ncbi.nlm.nih.gov/pubmed/24681962
http://dx.doi.org/10.1038/bcj.2014.18