The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia

The hypoxia-inducible factor (HIF) family of transcription factors coordinates diverse cellular and systemic responses to hypoxia. Chuvash polycythemia (CP) is an autosomal recessive disorder in humans in which there is impaired oxygen-dependent degradation of HIF, resulting in long-term systemic el...

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Detalles Bibliográficos
Autores principales: Slingo, Mary E., Turner, Philip J., Christian, Helen C., Buckler, Keith J., Robbins, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972741/
https://www.ncbi.nlm.nih.gov/pubmed/24030664
http://dx.doi.org/10.1152/japplphysiol.00530.2013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972741/
https://www.ncbi.nlm.nih.gov/pubmed/24030664
http://dx.doi.org/10.1152/japplphysiol.00530.2013

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