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β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein

Chronic neuroinflammation is an integral pathological feature of major neurodegenerative diseases. The recruitment of microglia to affected brain regions and the activation of these cells are the major events leading to disease-associated neuroinflammation. In a previous study, we showed that neuron...

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Detalles Bibliográficos
Autores principales: Kim, Changyoun, Cho, Eun-Deok, Kim, Hyung-Koo, You, Sungyong, Lee, He-Jin, Hwang, Daehee, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972795/
https://www.ncbi.nlm.nih.gov/pubmed/24743837
http://dx.doi.org/10.1038/emm.2014.6