Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: implications for disease-dependent drug–drug interactions

We studied the impact of administering XPro1595, a novel antagonist of soluble tumor necrosis factor-α(TNFα), on the regulation of hepatic cytochrome P450 enzymes in the Citrobacter rodentium model of infectious colitis. XPro1595 was administered subcutaneously every 3 days throughout the infection,...

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Detalles Bibliográficos
Autores principales: Nyagode, Beatrice A, Jahangardi, Roya, Merrell, Matthew D, Tansey, Malú G, Morgan, Edward T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972819/
https://www.ncbi.nlm.nih.gov/pubmed/24707356
http://dx.doi.org/10.1002/prp2.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972819/
https://www.ncbi.nlm.nih.gov/pubmed/24707356
http://dx.doi.org/10.1002/prp2.27

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