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The Involvement of Calpain in CD4(+) T Helper Cell Bias in Multple Sclerosis

The pathogenesis of multiple sclerosis (MS) is mediated by massive infiltration of myelin-specific T cells into the central nervous system (CNS). Self-reactive CD4(+) T helper (Th) cells, specifically Th1 and Th17 cells, are hallmarks of active disease in progression, whereas Th2 cells are predomina...

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Detalles Bibliográficos
Autores principales: Trager, Nicole, Butler, Jonathan T, Haque, Azizul, Ray, Swapan K, Beeson, Craig, Banik, Naren L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972924/
https://www.ncbi.nlm.nih.gov/pubmed/24707444
http://dx.doi.org/10.4172/2155-9899.1000153