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The Involvement of Calpain in CD4(+) T Helper Cell Bias in Multple Sclerosis
The pathogenesis of multiple sclerosis (MS) is mediated by massive infiltration of myelin-specific T cells into the central nervous system (CNS). Self-reactive CD4(+) T helper (Th) cells, specifically Th1 and Th17 cells, are hallmarks of active disease in progression, whereas Th2 cells are predomina...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972924/ https://www.ncbi.nlm.nih.gov/pubmed/24707444 http://dx.doi.org/10.4172/2155-9899.1000153 |