A comparative study on the physicochemical and biological stability of IgG(1) and monoclonal antibodies during spray drying process

BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG(1) and a monoclonal antibody (trastuzumab) during the spray drying process was...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramezani, Vahid, Vatanara, Alireza, Najafabadi, Abdolhossein Rouholamini, Shokrgozar, Mohammad Ali, Khabiri, Alireza, Seyedabadi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972992/
https://www.ncbi.nlm.nih.gov/pubmed/24641877
http://dx.doi.org/10.1186/2008-2231-22-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972992/
https://www.ncbi.nlm.nih.gov/pubmed/24641877
http://dx.doi.org/10.1186/2008-2231-22-31

Ejemplares similares