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A comparative study on the physicochemical and biological stability of IgG(1) and monoclonal antibodies during spray drying process
BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG(1) and a monoclonal antibody (trastuzumab) during the spray drying process was...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972992/ https://www.ncbi.nlm.nih.gov/pubmed/24641877 http://dx.doi.org/10.1186/2008-2231-22-31 |