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Concurrent MCL1 and JUN amplification in pseudomyxoma peritonei: a comprehensive genetic profiling and survival analysis

Pseudomyxoma peritonei (PMP) is a rare abdominal malignancy. We hypothesized that next-generation exomic sequencing would identify recurrent mutations that may have prognostic or therapeutic implications. Ten patients were selected on the basis of availability of tissue and adequate follow-up. They...

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Detalles Bibliográficos
Autores principales: Sio, Terence T, Mansfield, Aaron S, Grotz, Travis E, Graham, Rondell P, Molina, Julian R, Que, Florencia G, Miller, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973125/
https://www.ncbi.nlm.nih.gov/pubmed/24369359
http://dx.doi.org/10.1038/jhg.2013.132