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The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma

Epithelial-to-mesenchymal transition (EMT) has an important role in invasion and metastasis of hepatocellular carcinoma (HCC). To explore the regulatory mechanism of atypical protein kinase C ι (aPKCι) signaling pathways to HCC development, and find an agent for targeted therapy for HCC, immortalize...

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Detalles Bibliográficos
Autores principales: Ma, C Q, Yang, Y, Wang, J M, Du, G S, Shen, Q, Liu, Y, Zhang, J, Hu, J L, Zhu, P, Qi, W P, Qian, Y W, Fu, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973203/
https://www.ncbi.nlm.nih.gov/pubmed/24651432
http://dx.doi.org/10.1038/cddis.2014.91