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Survivin is essential for fertile egg production and female fertility in mice

Survivin is the smallest member of the inhibitor of apoptosis protein (IAP) family and acts as a bifunctional protein involved in mitosis regulation and apoptosis inhibition. To identify the physiological role of Survivin in female reproduction, we selectively disrupted Survivin expression in oocyte...

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Detalles Bibliográficos
Autores principales: Jiang, Z-Z, Hu, M-W, Wang, Z-B, Huang, L, Lin, F, Qi, S-T, Ouyang, Y-C, Fan, H-Y, Schatten, H, Mak, T W, Sun, Q-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973204/
https://www.ncbi.nlm.nih.gov/pubmed/24675472
http://dx.doi.org/10.1038/cddis.2014.126