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Rapamycin delays salivary gland atrophy following ductal ligation

Salivary gland atrophy is a frequent consequence of head and neck cancer irradiation therapy but can potentially be regulated through the mammalian target of rapamycin (mTOR). Excretory duct ligation of the mouse submandibular gland provokes severe glandular atrophy causing activation of mTOR. This...

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Detalles Bibliográficos
Autores principales: Bozorgi, S S, Proctor, G B, Carpenter, G H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973210/
https://www.ncbi.nlm.nih.gov/pubmed/24675464
http://dx.doi.org/10.1038/cddis.2014.108