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Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus

Familial neurohypophysial diabetes insipidus (FNDI) characterized by progressive polyuria is mostly caused by mutations in the gene encoding neurophysin II (NPII), which is the carrier protein of the antidiuretic hormone, arginine vasopressin (AVP). Although accumulation of mutant NPII in the endopl...

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Detalles Bibliográficos
Autores principales: Hagiwara, D, Arima, H, Morishita, Y, Wenjun, L, Azuma, Y, Ito, Y, Suga, H, Goto, M, Banno, R, Sugimura, Y, Shiota, A, Asai, N, Takahashi, M, Oiso, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973212/
https://www.ncbi.nlm.nih.gov/pubmed/24675466
http://dx.doi.org/10.1038/cddis.2014.124