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Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus
Familial neurohypophysial diabetes insipidus (FNDI) characterized by progressive polyuria is mostly caused by mutations in the gene encoding neurophysin II (NPII), which is the carrier protein of the antidiuretic hormone, arginine vasopressin (AVP). Although accumulation of mutant NPII in the endopl...
Autores principales: | Hagiwara, D, Arima, H, Morishita, Y, Wenjun, L, Azuma, Y, Ito, Y, Suga, H, Goto, M, Banno, R, Sugimura, Y, Shiota, A, Asai, N, Takahashi, M, Oiso, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973212/ https://www.ncbi.nlm.nih.gov/pubmed/24675466 http://dx.doi.org/10.1038/cddis.2014.124 |
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