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D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation
Non-enzymatic glycation of proteins by reducing saccharides for instance D-glucose is an important post-translational modification regulating protein function. Already two centuries ago, D-glucose (Glc) was identified in the urine of diabetic patients. Recently, abnormally high level of D-ribose (Ri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973213/ https://www.ncbi.nlm.nih.gov/pubmed/24625976 http://dx.doi.org/10.1038/cddis.2014.89 |