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BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

BNIP3 is an atypical BH3-only member of the BCL-2 family of proteins with reported pro-death as well as pro-autophagic and cytoprotective functions, depending on the type of stress and cellular context. In line with this, the role of BNIP3 in cancer is highly controversial and increased BNIP3 levels...

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Detalles Bibliográficos
Autores principales: Maes, H, Van Eygen, S, Krysko, D V, Vandenabeele, P, Nys, K, Rillaerts, K, Garg, A D, Verfaillie, T, Agostinis, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973222/
https://www.ncbi.nlm.nih.gov/pubmed/24625986
http://dx.doi.org/10.1038/cddis.2014.94