Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks

The study of rare human syndromes characterized by radiosensitivity has been instrumental in identifying novel proteins and pathways involved in DNA damage responses to ionizing radiation. In the present study, a mutation in mitochondrial poly-A-polymerase (MTPAP), not previously recognized for its...

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Detalles Bibliográficos
Autores principales: Martin, N T, Nakamura, K, Paila, U, Woo, J, Brown, C, Wright, J A, Teraoka, S N, Haghayegh, S, McCurdy, D, Schneider, M, Hu, H, Quinlan, A R, Gatti, R A, Concannon, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973239/
https://www.ncbi.nlm.nih.gov/pubmed/24651433
http://dx.doi.org/10.1038/cddis.2014.99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973239/
https://www.ncbi.nlm.nih.gov/pubmed/24651433
http://dx.doi.org/10.1038/cddis.2014.99

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