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PUMA mediates ER stress-induced apoptosis in portal hypertensive gastropathy

Mucosal apoptosis has been demonstrated to be an essential pathological feature in portal hypertensive gastropathy (PHG). p53-upregulated modulator of apoptosis (PUMA) was identified as a BH3-only Bcl-2 family protein that has an essential role in apoptosis induced by a variety of stimuli, including...

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Detalles Bibliográficos
Autores principales: Tan, S, Wei, X, Song, M, Tao, J, Yang, Y, Khatoon, S, Liu, H, Jiang, J, Wu, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973242/
https://www.ncbi.nlm.nih.gov/pubmed/24625987
http://dx.doi.org/10.1038/cddis.2014.95