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Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?
Acquired resistance toward apoptosis represents one of the hallmarks of human cancer and a major cause of the inefficacy of most anticancer treatment regimens. Based on its ability to inhibit apoptosis, the B-cell lymphoma/leukemia 2 (Bcl-2) protein family has garnered the most attention as a promis...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973243/ https://www.ncbi.nlm.nih.gov/pubmed/24603326 http://dx.doi.org/10.1038/cddis.2014.61 |