Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells

Lysosomes are acidic organelles that have a crucial role in degrading intracellular macromolecules and organelles during the final stage of autophagy. Tetrandrine (Tet), a bisbenzylisoquinoline alkaloid, was reported as an autophagy activator. Here, in contrast with previous studies, we show that Te...

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Detalles Bibliográficos
Autores principales: Qiu, W, Su, M, Xie, F, Ai, J, Ren, Y, Zhang, J, Guan, R, He, W, Gong, Y, Guo, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973245/
https://www.ncbi.nlm.nih.gov/pubmed/24625982
http://dx.doi.org/10.1038/cddis.2014.84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973245/
https://www.ncbi.nlm.nih.gov/pubmed/24625982
http://dx.doi.org/10.1038/cddis.2014.84

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