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Targeting and tracing of specific DNA sequences with dTALEs in living cells

Epigenetic regulation of gene expression involves, besides DNA and histone modifications, the relative positioning of DNA sequences within the nucleus. To trace specific DNA sequences in living cells, we used programmable sequence-specific DNA binding of designer transcription activator-like effecto...

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Detalles Bibliográficos
Autores principales: Thanisch, Katharina, Schneider, Katrin, Morbitzer, Robert, Solovei, Irina, Lahaye, Thomas, Bultmann, Sebastian, Leonhardt, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973286/
https://www.ncbi.nlm.nih.gov/pubmed/24371265
http://dx.doi.org/10.1093/nar/gkt1348