Active site plasticity enables metal-dependent tuning of Cas5d nuclease activity in CRISPR-Cas type I-C system

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) in association with CRISPR-associated (Cas) proteins constitutes a formidable defense system against mobile genetic elements in prokaryotes. In type I-C, the ribonucleoprotein surveillance complex comprises only three Cas proteins, na...

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Detalles Bibliográficos
Autores principales: Punetha, Ankita, Sivathanu, Raveendran, Anand, Baskaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973291/
https://www.ncbi.nlm.nih.gov/pubmed/24371266
http://dx.doi.org/10.1093/nar/gkt1335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973291/
https://www.ncbi.nlm.nih.gov/pubmed/24371266
http://dx.doi.org/10.1093/nar/gkt1335

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