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A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation

Archease is a 16-kDa protein that is conserved in all three domains of life. In diverse bacteria and archaea, the genes encoding Archease and the tRNA ligase RtcB are localized into an operon. Here we provide a rationale for this operon organization by showing that Archease and RtcB from Pyrococcus...

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Detalles Bibliográficos
Autores principales: Desai, Kevin K., Cheng, Chin L., Bingman, Craig A., Phillips, George N., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973293/
https://www.ncbi.nlm.nih.gov/pubmed/24435797
http://dx.doi.org/10.1093/nar/gkt1375