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Redirecting splicing with bifunctional oligonucleotides

Ectopic modulators of alternative splicing are important tools to study the function of splice variants and for correcting mis-splicing events that cause human diseases. Such modulators can be bifunctional oligonucleotides made of an antisense portion that determines target specificity, and a non-hy...

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Detalles Bibliográficos
Autores principales: Brosseau, Jean-Philippe, Lucier, Jean-François, Lamarche, Andrée-Anne, Shkreta, Lulzim, Gendron, Daniel, Lapointe, Elvy, Thibault, Philippe, Paquet, Éric, Perreault, Jean-Pierre, Abou Elela, Sherif, Chabot, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973305/
https://www.ncbi.nlm.nih.gov/pubmed/24375754
http://dx.doi.org/10.1093/nar/gkt1287