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Dicer-related helicase 3 forms an obligate dimer for recognizing 22G-RNA

Dicer is a specialized nuclease that produces RNA molecules of specific lengths for use in gene silencing pathways. Dicer relies on the correct measurement of RNA target duplexes to generate products of specific lengths. It is thought that Dicer uses its multidomain architecture to calibrate RNA pro...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Megan E., Vela, Adriana, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973318/
https://www.ncbi.nlm.nih.gov/pubmed/24435798
http://dx.doi.org/10.1093/nar/gkt1383