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Multiple-binding-site mechanism explains concentration-dependent unbinding rates of DNA-binding proteins

Recent work has demonstrated concentration-dependent unbinding rates of proteins from DNA, using fluorescence visualization of the bacterial nucleoid protein Fis [Graham et al. (2011) (Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA. Nucleic Acids Res.,...

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Detalles Bibliográficos
Autores principales: Sing, Charles E., Olvera de la Cruz, Monica, Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973338/
https://www.ncbi.nlm.nih.gov/pubmed/24393773
http://dx.doi.org/10.1093/nar/gkt1327