RecA-dependent programmable endonuclease Ref cleaves DNA in two distinct steps

The bacteriophage P1 recombination enhancement function (Ref) protein is a RecA-dependent programmable endonuclease. Ref targets displacement loops formed when an oligonucleotide is bound by a RecA filament and invades homologous double-stranded DNA sequences. Mechanistic details of this reaction ha...

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Detalles Bibliográficos
Autores principales: Ronayne, Erin A., Cox, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973344/
https://www.ncbi.nlm.nih.gov/pubmed/24371286
http://dx.doi.org/10.1093/nar/gkt1342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973344/
https://www.ncbi.nlm.nih.gov/pubmed/24371286
http://dx.doi.org/10.1093/nar/gkt1342

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