Clonal selection and therapy resistance in acute leukaemias: mathematical modelling explains different proliferation patterns at diagnosis and relapse

Recent experimental evidence suggests that acute myeloid leukaemias may originate from multiple clones of malignant cells. Nevertheless, it is not known how the observed clones may differ with respect to cell properties, such as proliferation and self-renewal. There are scarcely any data on how thes...

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Detalles Bibliográficos
Autores principales: Stiehl, Thomas, Baran, Natalia, Ho, Anthony D., Marciniak-Czochra, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973374/
https://www.ncbi.nlm.nih.gov/pubmed/24621818
http://dx.doi.org/10.1098/rsif.2014.0079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973374/
https://www.ncbi.nlm.nih.gov/pubmed/24621818
http://dx.doi.org/10.1098/rsif.2014.0079

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