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Mathematical modelling of adult hippocampal neurogenesis: effects of altered stem cell dynamics on cell counts and bromodeoxyuridine-labelled cells

In the adult hippocampus, neurogenesis—the process of generating mature granule cells from adult neural stem cells—occurs throughout the entire lifetime. In order to investigate the involved regulatory mechanisms, knockout (KO) experiments, which modify the dynamic behaviour of this process, were co...

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Detalles Bibliográficos
Autores principales: Ziebell, Frederik, Martin-Villalba, Ana, Marciniak-Czochra, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973376/
https://www.ncbi.nlm.nih.gov/pubmed/24598209
http://dx.doi.org/10.1098/rsif.2014.0144