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Intravitreal Injection of IGFBP-3 Restores Normal Insulin Signaling in Diabetic Rat Retina
Diabetes-induced changes in growth factor binding protein 3 (IGFBP-3) and tumor necrosis factor alpha (TNFα) have been linked to decreased insulin receptor signaling in diabetic retinopathy. Our previous studies in retinas of diabetic rats have shown that Compound 49b, a novel β-adrenergic receptor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973588/ https://www.ncbi.nlm.nih.gov/pubmed/24695399 http://dx.doi.org/10.1371/journal.pone.0093788 |