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The Binding of Monomeric C-Reactive Protein (mCRP) to Integrins αvβ3 and α4β1 Is Related to Its Pro-Inflammatory Action

The prototypic acute phase reactant C-reactive protein (CRP) is not only a marker but also a potential contributor to inflammatory diseases. CRP exists as the circulating native, pentameric CRP (pCRP) and the monomeric isoform (mCRP), formed as a result of a dissociation process of pCRP. mCRP is hig...

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Detalles Bibliográficos
Autores principales: Fujita, Masaaki, Takada, Yoko K., Izumiya, Yoshihiro, Takada, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973595/
https://www.ncbi.nlm.nih.gov/pubmed/24695572
http://dx.doi.org/10.1371/journal.pone.0093738