Distinct transthyretin oxidation isoform profile in spinal fluid from patients with Alzheimer’s disease and mild cognitive impairment

BACKGROUND: Transthyretin (TTR), an abundant protein in cerebrospinal fluid (CSF), contains a free, oxidation-prone cysteine residue that gives rise to TTR isoforms. These isoforms may reflect conditions in vivo. Since increased oxidative stress has been linked to neurodegenerative disorders such as...

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Detalles Bibliográficos
Autores principales: Poulsen, Keld, Bahl, Justyna MC, Simonsen, Anja H, Hasselbalch, Steen G, Heegaard, Niels HH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973606/
https://www.ncbi.nlm.nih.gov/pubmed/24678637
http://dx.doi.org/10.1186/1559-0275-11-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973606/
https://www.ncbi.nlm.nih.gov/pubmed/24678637
http://dx.doi.org/10.1186/1559-0275-11-12

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