Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from Kras(G12D) Mice by Inhibiting Akt and Sonic Hedgehog Pathways

Pancreatic cancer is a deadly disease, and therefore effective treatment and/or prevention strategies are urgently needed. The objectives of this study were to examine the molecular mechanisms by which embelin inhibited human pancreatic cancer cell growth in vitro, and xenografts in Balb C nude mice...

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Detalles Bibliográficos
Autores principales: Huang, Minzhao, Tang, Su-Ni, Upadhyay, Ghanshyam, Marsh, Justin L., Jackman, Christopher P., Shankar, Sharmila, Srivastava, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973629/
https://www.ncbi.nlm.nih.gov/pubmed/24694877
http://dx.doi.org/10.1371/journal.pone.0092161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973629/
https://www.ncbi.nlm.nih.gov/pubmed/24694877
http://dx.doi.org/10.1371/journal.pone.0092161

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