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Epigenetic Silencing of TFPI-2 in Canine Diffuse Large B-Cell Lymphoma
Epigenetic modifications are important early events during carcinogenesis. In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that contributes to cancer development and progression. Tissue factor pathway inhibit...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973630/ https://www.ncbi.nlm.nih.gov/pubmed/24695110 http://dx.doi.org/10.1371/journal.pone.0092707 |