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Synergistic Effects of Targeted PI3K Signaling Inhibition and Chemotherapy in Liposarcoma

While liposarcoma is the second most common soft tissue malignant tumor, the molecular pathogenesis in this malignancy is poorly understood. Our goal was therefore to expand the understanding of molecular mechanisms that drive liposarcoma and identify therapeutically-susceptible genetic alterations....

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Detalles Bibliográficos
Autores principales: Guo, Shang, Lopez-Marquez, Hector, Fan, Kenneth C., Choy, Edwin, Cote, Gregory, Harmon, David, Nielsen, G. Petur, Yang, Cao, Zhang, Changqing, Mankin, Henry, Hornicek, Francis J., Borger, Darrell R., Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973642/
https://www.ncbi.nlm.nih.gov/pubmed/24695632
http://dx.doi.org/10.1371/journal.pone.0093996