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TGF-β Signaling Regulates Neuronal C1q Expression and Developmental Synaptic Refinement

Immune molecules, including complement proteins C1q and C3, have emerged as critical mediators of synaptic refinement and plasticity. Complement localizes to synapses and refines the developing visual system via C3-dependent microglial phagocytosis of synapses. Retinal ganglion cells (RGCs) express...

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Detalles Bibliográficos
Autores principales: Bialas, Allison R., Stevens, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973738/
https://www.ncbi.nlm.nih.gov/pubmed/24162655
http://dx.doi.org/10.1038/nn.3560