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Landscape and variation of RNA secondary structure across the human transcriptome

In parallel to the genetic code for protein synthesis, a second layer of information is embedded in all RNA transcripts in the form of RNA structure. RNA structure influences practically every step in the gene expression program(1). Yet the nature of most RNA structures or effects of sequence variat...

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Detalles Bibliográficos
Autores principales: Wan, Yue, Qu, Kun, Zhang, Qiangfeng Cliff, Flynn, Ryan A., Manor, Ohad, Ouyang, Zhengqing, Zhang, Jiajing, Spitale, Robert C., Snyder, Michael P., Segal, Eran, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973747/
https://www.ncbi.nlm.nih.gov/pubmed/24476892
http://dx.doi.org/10.1038/nature12946