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Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis

BACKGROUND: Studies of twin pairs discordant for autoimmune conditions provide a unique opportunity to explore contributing factors triggered by complex gene-environment interactions. METHODS: In this cross-sectional study, thirty-one monozygotic or dizygotic twin pairs discordant for myositis or sy...

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Detalles Bibliográficos
Autores principales: Gan, Lu, O’Hanlon, Terrance P, Gordon, Aaron S, Rider, Lisa G, Miller, Frederick W, Burbelo, Peter D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973849/
https://www.ncbi.nlm.nih.gov/pubmed/24602337
http://dx.doi.org/10.1186/1471-2474-15-67