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Label-free drug discovery

Current drug discovery is dominated by label-dependent molecular approaches, which screen drugs in the context of a predefined and target-based hypothesis in vitro. Given that target-based discovery has not transformed the industry, phenotypic screen that identifies drugs based on a specific phenoty...

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Detalles Bibliográficos
Autor principal: Fang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973898/
https://www.ncbi.nlm.nih.gov/pubmed/24723889
http://dx.doi.org/10.3389/fphar.2014.00052