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Multiple functions of G protein-coupled receptor kinases

Desensitization is a physiological feedback mechanism that blocks detrimental effects of persistent stimulation. G protein-coupled receptor kinase 2 (GRK2) was originally identified as the kinase that mediates G protein-coupled receptor (GPCR) desensitization. Subsequent studies revealed that GRK is...

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Detalles Bibliográficos
Autores principales: Watari, Kenji, Nakaya, Michio, Kurose, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973964/
https://www.ncbi.nlm.nih.gov/pubmed/24597858
http://dx.doi.org/10.1186/1750-2187-9-1